Blood-Brain Barrier - Another Win?

Blood-Brain Barrier - Another Win?
18X24 Acrylic painting on Acrylic Panel

As I mentioned in the earlier "Journey with Alzheimer's" post, I will begin my first Leqembi® infusion on Thursday, February 1st, and will continue them on a bi-weekly basis for 18 months.

Researchers are exploring the use of ultrasound to temporarily open the blood-brain barrier (BBB) to enhance the delivery of drugs like Leqembi to the brain, specifically targeting the removal of amyloid protein plaques associated with conditions like Alzheimer's disease.

The blood-brain barrier is a protective mechanism that limits the entry of certain substances, including drugs, into the brain. This barrier is essential for maintaining the brain's microenvironment and protecting it from potential toxins. However, in the context of treating neurodegenerative diseases, finding ways to safely and temporarily open the BBB could improve drug delivery and efficacy.

This painting captures the idea of breaking through this protective barrier to enable the drug to better target and dissolve amyloid protein plaques, and the merging of scientific innovation with the quest for effective treatments for neurodegenerative diseases.